Fig. 7: Levels of lipids and metabolites in plasma of TMEM175 patients correlated with PD endophenotypes. | npj Parkinson's Disease

Fig. 7: Levels of lipids and metabolites in plasma of TMEM175 patients correlated with PD endophenotypes.

From: Multiomics approach identifies dysregulated lipidomic and proteomic networks in Parkinson’s disease patients mutated in TMEM175

Fig. 7: Levels of lipids and metabolites in plasma of TMEM175 patients correlated with PD endophenotypes.

a, b Graphical representation of the significant negative correlation of the levels of PC and PI 34:1|PI 16:0_18:1 with age and age at onset (AAO) in PD_TMEM175 patients. c L-Glutamic acid showed a significant positive correlation with UPDRS, NMS and D6 Gastrointestinal trait score in PD_TMEM175 patients. Correlation was evaluated with Pearson analysis and p-value was corrected with Bonferroni multiple testing. r and p-value (p) were reported in the graph for each analysis.

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