Table 1 Demographic comparison between PD-FOG and PD-nFOG groups in cohort 1

From: Atrophy of ventral diencephalon is associated with freezing of gait in Parkinson’s disease: analysis of two cohorts

Characteristics

PD-FOG (N = 153)

PD-nFOG (N = 163)

P value

Age at admission, years, median (IQR)

69 (60–75)

65 (57–69)

0.002

Sex, n (F/M)

66/87

68/95

0.799

BMI, kg/m2, mean ± SD

24.15 ± 3.07

24.05 ± 3.09

0.772

Disease profiles

 Disease duration, months, median (IQR)

7 (4–10)

5 (3–9)

0.001

 Hoehn–Yahr stage, median (IQR)

3 (2.5–4)

3 (2–3)

<0.001

 Levodopa daily dosage at admission, mg, median (IQR)

500 (300–687.5)

300 (200–545.5)

<0.001

 MDS-UPDRS III, median (IQR)

46 (28–60)

36 (25–48)

<0.001

 MMSE, median (IQR)

27 (22–29)

27 (25–29)

0.564

 MoCA, median (IQR)

21 (17–25)

22 (19–25)

0.066

 HAMA, median (IQR)

9 (5–14)

8 (5–12)

0.131

 HAMD, median (IQR)

9 (6–13)

8 (5–14)

0.341

White matter hyperintensity

 Periventricular Fazekas rating scale, median (IQR)

1 (0–2)

1 (0–2)

0.780

 Deep Fazekas rating scale, median (IQR)

1 (1–2)

1 (1–1)

0.120

 FOG severity, median (IQR)

3 (2–4)

0 (0–0)

<0.001

  1. BMI body mass index, IQR interquartile range, HAMA Hamilton anxiety scale, HAMD Hamilton depression scale, MDS-UPDRS III movement disorder society united Parkinson’s disease rating scale part III, MMSE mini-mental state examination, MoCA Montreal cognitive assessment, SD standard deviation.
  2. Bold values identify statistical significance (P < 0.05).
Back to article page