Table 2 Results of the main analysis of incident PD risk vs principal components of air pollutants exposure

From: Prominent role of PM10 in the link between air pollution and incident Parkinson’s Disease

HR [95% CI] Model 1

HR [95% CI] Model 2

HR [95% CI] Model 3

HR [95% CI] Model 4

Exposure

Tagged pollutants

1.04 [1.02–1.06]

1.05 [1.02–1.07]

1.05 [1.03–1.07]

1.04 [1.02–1.07]

PC1

PM10

1.02 [0.99–1.04]

1.01 [0.98–1.04]

1.01 [0.98–1.04]

1.00 [0.97–1.04]

PC2

O3/CO/SO2

0.99 [0.95–1.03]

0.99 [0.95–1.03]

0.99 [0.95–1.03]

0.99 [0.95–1.03]

PC3

NOx/BTX hydrocarbons

  1. Hazard Ratios and 95% confidence intervals HR [95% CI] are reported for each model and each PC score tested, while association p-value is reported only for the most adjusted model (see below). Significant associations surviving Bonferroni correction for multiple testing of three PC scores (α = 0.017) are highlighted in bold. Model 1: age and sex; Model 2: Model 1 + education level completed + professional exposure to toxic compounds and working class; Model 3: Model 2 + smoking status; Model 4: Model 3 + urban living. Legend: PM10 = particulate matter with aerodynamic diameter <10 μm; NOx nitrogen oxides, SO2 sulfur dioxide, CO Carbon monoxide, O3 ozone, BTX hydrocarbons benzene, toluene and xylene.
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