Table 2 Intergroup differences in neuropsychological data between iRBD patients and HC

From: Clinical and brain volumetric correlates of decreased DTI-ALPS, suggestive of local glymphatic dysfunction, in iRBD

Test

N

iRBD

HC

Statistic

P value

Effect size

Clock drawing test

21/60

12.43 (2.47)

13.48 (1.63)

0.749

0.389

 

Clock copying test

21/60

14.13 (0.98)

14.57 (0.6)

2.327

0.131

 

Digit span forward

21/60

5.23 (1.23)

6.09 (1.09)

5.589

0.021

0.722

Digit span backwards

21/60

4.03 (1.18)

4.48 (0.93)

1.959

0.166

 

Span forward-backwards

21/60

1.20 (1.35)

1.62 (0.74)

1.008

0.317

 

BJLO

21/60

22.7 (5.53)

25.62 (3.40)

5.881

0.018

0.575

SDMT

21/60

40.3 (13.85)

51.1 (9.96)

7.609

0.007

0.832

BFRT

21/60

22.07 (2.25)

22.81 (1.94)

1.005

0.319

 

Stroop, Word

21/58

86.97 (18.52)

100.1 (20.82)

5.197

0.025

0.686

Stroop, Color

21/58

55.09 (15.21)

64.52 (12.31)

2.047

0.157

 

Stroop, Word-Color

21/58

31.26 (11.21)

36.81 (8.79)

0.947

0.334

 

Fluency (animals)

21/60

18.88 (5.66)

23.24 (4.81)

5.098

0.027

0.798

Fluency (p)

21/60

13.27 (5.56)

15.67 (5.09)

0.561

0.456

 

BNT

21/60

13.62 (1.04)

13.81 (1.29)

0.010

0.919

 

TMT A

20/50

50.95 (26.54)

39.24 (15.51)

1.425

0.236

 

TMT B

20/50

115.76 (70.24)

89.05 (32.87)

1.699

0.197

 

TMT B-A

20/50

71.80 (62.09)

50.35 (28.39)

1.385

0.243

 

Similarities (WAIS-IV)

21/60

19.18 (5.86)

22.05 (5.22)

1.303

0.257

 

Warrington Recognition Memory for Faces

21/60

40.57 (6.48)

42.3 (4.84)

0.811

0.371

 

RAVLT, Trial 1

21/60

4.62 (1.6)

4.95 (1.77)

0.039

0.844

 

RAVLT, Total

21/60

39.08 (10.5)

44.81 (8.12)

0.517

0.474

 

RAVLT, delayed recall

21/60

7.75 (3.39)

9.38 (2.71)

0.669

0.416

 

GPT, dominant hand

18/58

106.86 (68.66)

79.33 (15)

0.909

0.344

 

GPT, non-dominant hand

18/58

112.97 (37.74)

89.94 (15.97)

5.214

0.025

-0.677

UPSIT-40

23/62

19.65 (6.36)

29.43 (4.26)

27.941

<0.001*

1.665

FM-100 Hue Test, Total Error Score

17/51

173.31 (96.1)

148.47 (47.94)

0.105

0.747

 
  1. BNT Boston Naming Test, BFRT Benton’s Facial Recognition Test, BJLO Benton’s Judgement of Line Orientation Test, FM-100 Hue Test the Farnsworth-Munsell 100 Hue Test, HC healthy controls, iRBD isolated rapid-eye-movement sleep behavior disorder, GPT Grooved Pegboard Test, RAVLT Rey Auditory Verbal Learning Test, SDMT Symbol-Digit Modality Test- oral version, UPSIT-40 University of Pennsylvania Smell Identification Test, 40 items, WAIS-IV Weschler Adult Intelligence Scale – 4th version. Data are presented as mean and standard deviations. Group differences in cognitive tests were tested using ANCOVA analyses using sex and years of education as covariates. Non-adjusted p values are presented. Asterisks indicate those contrasts that survived FDR-correction for multiple comparisons. Effect sizes are reported as Cohen’s d.
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