Table 2 Comparison of the model’s performance showing the median AUC over 20 repeats of nested cross-validation, using all data modalities and each modality separately

From: Predicting dementia in people with Parkinson’s disease

Modality

Random forest

XGBoost

Logistic regression

Median AUC

P-value

Median AUC

P-value

Median AUC

P-value

Multimodal

0.62 (0.005)

0.60 (0.009)

0.62 (0.006)

Demographics + Genetics

0.61 (0.004)

<0.05

0.59 (0.007)

<0.05

0.61 (0.006)

<0.05

Demographics

0.56 (0.005)

<0.05

0.54 (0.008)

<0.05

0.57 (0.004)

<0.05

Genetics

0.58 (0.003)

<0.05

0.56 (0.008)

<0.05

0.58 (0.05)

<0.05

Comorbidities

0.58 (0.004)

<0.05

0.57 (0.004)

<0.05

0.57 (0.03)

<0.05

Lifestyle

0.49 (0.01)

<0.05

0.5 (0.009)

<0.05

0.49 (0.005)

<0.05

Environmental

0.51 (0.007)

<0.05

0.51 (0.008)

<0.05

0.5 (0.006)

<0.05

Family history

0.49 (0.01)

<0.05

0.49 (0.01)

<0.05

0.49 (0.006)

<0.05

  1. A Kruskal–Wallis test was used to determine if there were statistically significant differences in performance after the removal of each modality compared to the full model.