Fig. 1: Levels of SERPIN E1 in CSF of patients and controls.
From: Elevated cerebrospinal fluid levels of SERPIN E1 in participants with lewy body diseases
Levels of SERPIN E1 in CSF are compared between controls (CON) (blue dots) and patients with Parkinson’s disease (PD) (green dots) and Dementia with Lewy Bodies (DLB) (red dots) (Fig. 2A), between CON and PD/DLB patients without GBA1 variants (wildtype, WT) (Fig. 2B), and between CON and PD/DLB patients with GBA1 variants (Fig. 2C). There was a significant difference between the three cohorts regarding CSF SERPIN E1 levels with the highest levels in DLB total cohort, followed by PD total cohort and CON.
