Fig. 1: Model structure and key results. | npj Parkinson's Disease

Fig. 1: Model structure and key results.

From: Physical activity and network attack tolerance preserve motor function in Parkinson’s disease: A pilot study

Fig. 1

A Results of the generalized linear mixed models estimating the effect of biological (putamen dopamine terminal (DaT) integrity) and reserve factors (education and physical activity (PA)) on NAT. The arrows are color-coded and represent the direction of the association between NAT of the respective network and the covariate. The attention network (ATN) is shown in purple, and the somatomotor network (SMN) in turquoise. The surface projections depict the ROIs included for the somatomotor network (SMN, turquoise), the frontoparietal network (FPN, yellow), the attention network (ATN, green), the default mode network (DMN, red), and the global network (blue). B Results of the regression models. Top: Regression model predicting general cognitive performance (GCP) using education as a moderator. Bottom: Regression model predicting general motor performance (GMP) using PA as a moderator. The plus sign indicates a positive effect exerted by NAT (corresponding network also in red) and PA as a moderator on GMP. *Control variables for moderation analyses: age, sex, putaminal DaT, education or PA. For better visualization, effects of the control variables are not shown in both illustrations.

Back to article page