Table 1 Patient Demographics and Baseline Values
From: Faecal microbiota transplant in Parkinson’s disease: pilot study to establish safety & tolerability
Baseline Characteristics | n = 12 |
|---|---|
Male Patients | 8 (66%) |
Age at enrolment (years) | 69.5 (4.3) |
Age at diagnosis (years) | 62.6 (5.7) |
BMI | 25.0 (5.6) |
Disease duration at enrolment, (years) | 6.9 (2.4) |
Medications | |
- L-dopa equivalent daily dose (mg) - Dopamine agonist - Monoamine oxidase inhibitors - COMT inhibitors | 684 (431) 8 (67%) 7 (58%) 4 (33%) |
Comorbidities | |
- Diabetes - Hypertension - Depression - Anxiety | 2 (17%) 3 (25%) 4 (33%) 5 (42%) |
Parkinson’s symptoms | |
- Tremor - Rigidity - Akinesia/Bradykinesia - Freezing of gait - Constipation | 10 (83%) 11 (92%) 12 (100%) 3 (25%) 7 (58%) |
Montreal Cognitive Assessment | 27.3 (1.3) |
Parkinson’s Disease Severity Metrics | |
- UPDRS 1 - UPDRS 2 - UPDRS 4 - UPDRS 3: OFF-state - UPDRS 3: ON-state - Hauser Motor Diary (OFF time/24 h) | 2.3 (1.6) 21.4 (8.0) 6.3 (1.8) 28.3 (12.5) 12.7 (8.3) 4.8 (2.2) |
