Fig. 1: Manhattan plot of PD with RBD vs. PD without RBD. | npj Parkinson's Disease

Fig. 1: Manhattan plot of PD with RBD vs. PD without RBD.

From: Genome-wide association study of REM sleep behavior disorder in Parkinson’s disease

Fig. 1: Manhattan plot of PD with RBD vs. PD without RBD.The alternative text for this image may have been generated using AI.

A Manhattan plot showing the results of the GWAS meta-analysis, comparing PD with RBD and PD without RBD, highlighting the SNCA and LRRK2 loci. The Y axis represents the negative logarithm of p value, the X axis represents the chromosomal position of the variants and each dot on the figure represents a SNP. The red line represents the genome-wide Bonferroni-corrected statistical significance threshold (5 × 10−8), whereas the blue line is the false-discovery rate-corrected significance threshold (5 × 10−5). Chr chromosome, PD Parkinson’s disease, RBD REM sleep behavior disorder.

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