Table 3 Description of data sources and filtering conditions

From: Neural networks reveal novel gene signatures in Parkinson disease from single-nuclei transcriptomes

Dataset

Description

Source

Filtering thresholds

Kamath et al. 10

snRNAseq human midbrain

https://singlecell.broadinstitute.org/single_cell/study/SCP1768

Minimum UMI per cell: 650

Wang et al. 11

snRNAseq human midbrain

GEO; GSE184950

Minimum features per cell: 200; maximum features per cell: 2500

Smajic et al. 12

snRNAseq human midbrain

GEO; GSE157783

Minimum UMI per cell: 1500; minimum features per cell: 1000

Martirosyan et al. 45

snRNAseq human midbrain

GEO; GSE243639

Minimum UMI per cell: 500

FOUNDIN-PD; Bressan et al. 35

iPSC-derived DaNeurons

www.ppmi-info.org/access-dataspecimens/download-data; SCR 006431

Minimum features per cell: 1000; maximum features per cell: 9000

  1. Cells were filtered according to the thresholds defined in the corresponding manuscripts.
  2. GEO Gene Expression Omnibus, snRNAseq single nuclei RNA sequencing, UMI unique molecular identifier.
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