Fig. 5: Evaluation of plasmatic NfL in the study cohort.
From: JNK3 quantification in plasma: a novel biomarker for neuronal damage in Parkinson’s disease
A Plot of plasmatic log(NfL) concentration measured by SIMOA technology in HC and pathological groups. Each dot represents a patient and bars the median of the group. (B, upper panel) Multivariate multinomial and (B, lower panel) ordinal logistic regression analyses to assess the OR and 95% CI for NfL, age, and sex among pathological groups. An OR > 1 indicates an increased likelihood of pathological diagnosis. C Correlation between log(NfL) and age in all participants. D Correlation between log(NfL) and H&Y in De Novo and Late PD groups. E Correlation between log(NfL) and BDI-II in Late PD group. For all correlations, the regression line is reported together with its 95% CI (dashed line).
