Table 1 MSCs express many surface markers and secrete many proteins, immune modulating molecules and microRNAs.
From: Mesenchymal stem cell perspective: cell biology to clinical progress
Surface markers and cytokine receptors | Secreted growth factors and cytokines | Immunomodul-atory molecules | Micro RNAs |
|---|---|---|---|
CD9 | VEGF | TGF | miRNA-9-5p |
CD44 HA Rec | FGF2 | HGF | miRNA-10a |
CD54 ICAM-1 | FLT-3 Ligand | PGE2 antibac too | miRNA-10b |
CD58 LFA-3 | M-CSF | IL-1RA | miRNA-21 |
CD62L L-Selectin | G-CSF | IL-6 | miRNA-23b |
CD71 Transferrin Rec | GM-CSF inducible | IL10 | miRNA-24 |
CD73 Ectonucleotidase | SCF | LIF | miRNA-29 |
CD90 Thy-1 | LIF | HLA-G | miRNA-125b |
CD105 Endoglin | IDO | miRNA-133b | |
CD106 VCAM-1 | iNOS | miRNA-143-3p | |
CD117 KIT | TSG-6 | miRNA-145 | |
CDw119 IFNγR | Gal-1 | miRNA-146b | |
CD120a TNFIR | Gal-9 | miRNA-191-5p | |
CD120b TNFIIR | HO-1 | miRNA-199 | |
CD140b PDGFRB | LL37 antibac pep | let-7a-5p | |
CD146 MCAM | miRNA-222-3p | ||
CD166 IGF1R | miRNA-451 | ||
CD221 IGF1R | Integrins-positive | miRNA-486-5p | |
CD222 IGF2R | CD49a α1 | miRNA-1224 | |
CD331 FGFR1 | CD49b α2 | ||
CD332 FGFR2 | CD49c α3 | Integrins-negative | Hemato-negative |
SSEA-3 | CD49e αv | CD11a αL | CD4 |
SSEA-4 | CD51 aα | CD18 Cβ2 | CD11b |
HLA Class I | CD29 β1 | CD49d α4 | CD14 |
HLA-G | CD61 β3 | CD34 | |
(HLA Class II -inducible) | CD104 β4 | CD45 |
