Fig. 2: Muscle regeneration in Acomys.

Representative images of Mus (a, b) and Acomys (c, d) muscle after repeated injections of myotoxin. Acomys muscle regenerates perfectly and looks similar to uninjured tissue whereas in Mus, myofibrils are replaced with adipose tissue. Accumulation of adipose tissue in Mus is reflected in white regions of Trichrome stain (a, scale bar = 50 µm) and immunolabeled perilipin, a marker for adipocytes as indicated by white arrows (b, scale bar = 100 µm). Green = perilipin, blue = nuclei. Image adapted from Maden et al.⁶ under Creative Commons Attribution 4.0 International License.