Fig. 5: Shared genes dysregulated in gemin3, gemin5, and smn1 mutants revealed by RNA-Seq. | npj Regenerative Medicine

Fig. 5: Shared genes dysregulated in gemin3, gemin5, and smn1 mutants revealed by RNA-Seq.

From: A subset of SMN complex members have a specific role in tissue regeneration via ERBB pathway-mediated proliferation

Fig. 5

a Hierarchical clustering of RNA-Seq samples using log2-fold change of normalized read counts. The control and mutant embryos used for the analysis were: smn1fh229 (s1), gemin2hg108 (g2), gemin3hg105 (g3), gemin4hg109 (g4), gemin5hg80 (g5), gemin6hg110 (g6), and gemin7hg111 (g7). The Y-axis shows the linkage value. b and c Log2-fold change of mRNA expression of erbb2 b and erbb3b c in different homozygous mutant backgrounds. Error bars indicate standard deviations.

Back to article page