Fig. 1: Schematic representation of nephrogenesis, starting with the interaction of the cap mesenchyme (CM) and ureteric bud (UB) in the nephrogenic zone. | npj Regenerative Medicine

Fig. 1: Schematic representation of nephrogenesis, starting with the interaction of the cap mesenchyme (CM) and ureteric bud (UB) in the nephrogenic zone.

From: Defining the variety of cell types in developing and adult human kidneys by single-cell RNA sequencing

Fig. 1

Differentiation takes place along morphologically determined stages known as pretubular aggregate (PTA), comma-shaped body (CSB), renal vesicle (RV), S-shaped body (SSB), and capillary loop stage (CLS) nephron. The mature nephron is located throughout the cortex, whereas the Loop of Henle and collecting duct extend into the medulla.

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