Fig. 7: Mapping of reported read-outs for preclinical TEVG assessment and patency assessment methods.

a Number of studies reporting on read-outs; patency, cellularity, endothelialization, material degradation, collagen formation, elastin formation, calcification, and mechanical characterization. b Number of studies per patency assessment method; combination of both angiogram and ultrasound, angiogram, ultrasound, magnetic resonance imaging (MRI), macroscopic observation for pulsations distal to graft upon explantation, gross morphology upon explantation and histology, or not applicable (number of studies not reporting on patency).