Fig. 2: Morphology and characterization of surface-modified HS 3D scaffolds with LYN and HA via bioinspired dopamine chemistry. | npj Regenerative Medicine

Fig. 2: Morphology and characterization of surface-modified HS 3D scaffolds with LYN and HA via bioinspired dopamine chemistry.

From: Mussel-inspired multifunctional surface through promoting osteogenesis and inhibiting osteoclastogenesis to facilitate bone regeneration

Fig. 2: Morphology and characterization of surface-modified HS 3D scaffolds with LYN and HA via bioinspired dopamine chemistry.The alternative text for this image may have been generated using AI.

a Representative optical appearance and microstructure of different scaffolds after freeze-drying as observed by SEM and micro-CT. The blue arrows indicate the immobilization of LYN on the scaffold surface. b Average pore size, c porosity, and d WCA of the four kinds of scaffolds. e EDS mapping images and spectrum of HS@PDA-LYN/HA. f XRD spectra. g FTIR spectra. h TGA analysis of different scaffolds under a N2 atmosphere. i Representative stress–strain curve of scaffolds under compression. j Representative HPLC–MS/MS image of the HS@PDA-LYN/HA scaffold. k Accumulative LYN concentration released from HS@PDA-LYN/HA and HS@PDA-LYN/HA samples in Tris-HCl buffer solution. l Accumulative Ca ion concentration released from HS@PDA-LYN/HA samples in Tris-HCl buffer solution. Scale bar in a: from left to right 300, 20, 10 μm, 1 mm, in e: 250 μm. Data are expressed as the mean ± SD (n = 3). *P < 0.05 and **P < 0.01 indicate significant differences compared with the HS group. #P < 0.05 and # #P < 0.01 indicate significant differences compared with the HS@PDA-LYN/HA group.

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