Fig. 6: Biochemical analysis of liver and plasma marker levels for control, Tjp2 icKOHC, Yap icKOHC, and Tjp2 Yap icKOHC mice fed a 28-day DDC diet. | npj Regenerative Medicine

Fig. 6: Biochemical analysis of liver and plasma marker levels for control, Tjp2 icKOHC, Yap icKOHC, and Tjp2 Yap icKOHC mice fed a 28-day DDC diet.

From: ZO-2/Tjp2 suppresses Yap and Wwtr1/Taz-mediated hepatocyte to cholangiocyte transdifferentiation in the mouse liver

Fig. 6: Biochemical analysis of liver and plasma marker levels for control, Tjp2 icKOHC, Yap icKOHC, and Tjp2 Yap icKOHC mice fed a 28-day DDC diet.

a Plasma BA, (b) liver BA, (c) AP, (d) ALT, (e) AST, (f) Bilirubin. Data are shown as mean ± SD, unpaired Student’s t test. *p < 0.05; **p < 0.005, ***p < 0.0005, ns—not significant (p > 0.05), with p < 0.05 considered a significant difference. n = 7 mice per cohort. icKOHH, tamoxifen-induced hepatocyte deletion.

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