Fig. 4: Comparison of porcine niches to those in the human biliary tree (see also Table 1). | npj Regenerative Medicine

Fig. 4: Comparison of porcine niches to those in the human biliary tree (see also Table 1).

From: A postnatal network of co-hepato/pancreatic stem/progenitors in the biliary trees of pigs and humans

Fig. 4: Comparison of porcine niches to those in the human biliary tree (see also Table 1).

a A summary of the similarity of the stem cell and lineage cell markers between humans and pigs at both the gene level and protein level. b Paraffin sections of a 10% neutral-buffered-formalin-fixed and paraffin-embedded biliary tree tissue prepared from a 9-year-old, male human were used as positive controls for candidate antibodies screening and titration. H&E staining showed the preparation of the tissue preserved with the peribiliary glands (PBGs). c IHC staining for human biliary tree tissues of endodermal stem cell markers. IHC results with antibodies for porcine tissue study showed the PBGs expressed pluripotency markers (SOX2) and multiple endodermal stem cell markers (EpCAM and SOX9). Scale bars for low magnification images are 500 μm; for enlargement, images are 50 μm.

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