Fig. 2: hMSC survive in the SAMP peritoneum cavity up to day 9. | npj Regenerative Medicine

Fig. 2: hMSC survive in the SAMP peritoneum cavity up to day 9.

From: MSCs mediate long-term efficacy in a Crohn’s disease model by sustained anti-inflammatory macrophage programming via efferocytosis

Fig. 2

a Representative images showing time course BLI of transduced hMSCs in AKR and SAMP mice on days 0, 5, and 9. b Representative time course epifluorescence images of SAMP mice showing the presence of intraperitoneally administered NIR dye IVIS680 labeled hMSCs. Images were acquired on days 0, 9, and 28. c Quantitative estimation of total radiant efficiency in mice treated with IVIS680 tagged hMSCs. Data were expressed as mean ± SD from at least 2 independent experiments. P < 0.05 considered significant, by 1-way ANOVA. d Representative ex-vivo epifluorescence image of SAMP peritoneum cavity showing the presence of IVIS680 tagged hMSCs (yellow arrow) on day 9. e Flow cytometry gating scheme to detect hMSC cell population in the peritoneal lavage of hMSC administered SAMP at day 9.

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