Fig. 6: Expression of small, muscle-specific peptides across conditions. | npj Regenerative Medicine

Fig. 6: Expression of small, muscle-specific peptides across conditions.

From: Calorie restriction and rapamycin distinctly restore non-canonical ORF translation in the muscles of aging mice

Fig. 6: Expression of small, muscle-specific peptides across conditions.

a Myokine expression in samples from different conditions. Each dot represents a sample. P-values are from the Wald test from Deseq2 R package35. b Small peptides derived from transcripts initially annotated as lncRNAs. c Pattern of lncRNA-encoded ORF expression in age, CR and RM treatments. The heatmap shows the log2 fold-change in RPF numbers for the indicated lncRNAs from the noncode database (version 6)51. Shown is the numerical identifier of the lncRNA in the database, the start and end position of the ORF within the lncRNA. Only ORFs that have a significant change (p-value < 0.01, 50 lncRNAs) in at least one condition are represented.

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