Table 2 Effects of all combined cognitive enhancers on separate cognitive domains
From: Efficacy of different types of cognitive enhancers for patients with schizophrenia: a meta-analysis
Cognitive domain | Number of studies (k) | Patients (N) | ES Hedges’s g | (95% CI) | p-value | Q-statistic (df) | I 2 | Failsafe NR |
|---|---|---|---|---|---|---|---|---|
Overall cognition | 51 | 3635 | 0.10 | (0.01 to 0.18) | 0.023 | Q(50) = 70.84,p = 0.028 | 29.41 | 105 |
Attention | 71 | 4435 | 0.01 | (0.07 to 0.08) | 0.893 | Q(70) = 97.73,p = 0.016 | 28.38 | 0 |
PS | 71 | 4782 | 0.01 | (0.04 to 0.07) | 0.647 | Q(70) = 50.33,p = 0.963 | 0.00 | 0 |
Reasoning | 74 | 4492 | 0.02 | (−0.05 to 0.08) | 0.639 | Q(76) = 90.38,p = 0.082 | 19.22 | 0 |
Verbal fluency | 27 | 1134 | −0.05 | (−0.16 to 0.07) | 0.400 | Q(26) = 22.71,p = 0.649 | 0.000 | 0 |
Verbal L&M | 74 | 4190 | 0.03 | (−0.03 to 0.10) | 0.327 | Q(73) = 82.75,p = 0.204 | 11.79 | 0 |
Visual L&M | 66 | 4133 | 0.05 | (−0.02 to 0.11) | 0.155 | Q(65) = 67.04,p = 0.407 | 3.04 | 0 |
WM | 80 | 4649 | 0.06 | (−0.01 to 0.12) | 0.069 | Q(79) = 93.58,p = 0.125 | 15.58 | 0 |
