Table 2 Most significant differential expression genes between the weight and the no weight gain groups before medication

From: Altered gene expression in antipsychotic-induced weight gain

Gene symbol

Base mean weight gain

Base mean no weight gain

Log 2 fold change

Padj

GeneRif annotation

HBG1

184.32

1282.13

2.80

1.22E−83

CHOLEST

OTOF

213.17

55.78

−1.93

7.46E−62

 

IFI44L

3789.40

1598.25

−1.25

3.93E−28

 

SIGLEC1

2042.72

943.07

−1.12

6.56E−26

 

RSAD2

2611.27

1021.60

−1.35

2.85E−25

 

C21orf15

399.10

165.24

−1.27

6.80E−23

 

HBG2

1364.10

3524.10

1.37

1.54E−21

CHOLEST

NEBL

93.49

272.09

1.54

2.32E−21

 
  1. Gene symbol: official symbol; base mean weight gain: mean normalized counts from condition A; base mean no weight gain: mean normalized counts from condition B; base mean no weight gain: mean normalized counts from condition B; log 2 fold change: the logarithm, to basis 2, of the fold change; Padj: p value adjusted for multiple testing with the Benjamini–Hochberg procedure, which controls false discovery rate; GeneRif annotation: genes including the strings “BMI” or “cholest” in their GeneRIF definition
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