Table 5 Most significant differential expression genes between weight and no weight gain groups after medication

From: Altered gene expression in antipsychotic-induced weight gain

Gene symbol

Base mean weight gain

Base mean no weight gain

Log 2 fold change

Padj

GeneRif annotation

HBG1

145.94

622.58

2.09

1.42E−73

CHOLEST

MTRNR2L2

486.77

1001.34

1.04

3.70E−47

 

PRAME

29.23

2.13

−3.78

1.29E−25

 

MMP8

683.11

296.46

−1.20

5.05E−24

CHOLEST

CPA5

69.68

16.13

−2.11

5.73E−23

 

ETV7

167.26

372.19

1.15

6.64E−23

 

ANKRD22

191.43

395.08

1.05

6.50E−21

 
  1. Gene symbol: official symbol; base mean weight gain: mean normalized counts from condition A; base mean no weight gain: mean normalized counts from condition B; log 2 fold change: the logarithm, to basis 2, of the fold change; Padj: p value adjusted for multiple testing with the Benjamini–Hochberg procedure, which controls false discovery rate; GeneRif Annotation: Genes including the strings “BMI” or “cholest” in their GeneRIF definition
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