Table 2 Demographic characteristics of patients with schizophrenia with high 2DR occupancy medication, low D2R occupancy medication, and healthy controls.
From: Language disturbances in schizophrenia: the relation with antipsychotic medication
High D2R | Low D2R | HC | Test statistic | p-value | |
|---|---|---|---|---|---|
n | 23 | 18 | 40 | ||
Sex, male: female, n | 17:6 | 14:4 | 36:4 | χ2 = 3.038 | 0.219 |
Age, mean (SD) | 28.5 (9.04) | 28.3 (9.39) | 31.7 (11.71) | F(2,78) = 1.002 | 0.372 |
Years of education, mean (SD) | 13.2 (2.63) | 12.2 (2.94) | 14.8 (2.20) | F(2,77) = 7.446 | 0.001 |
Parental years of education, mean (SD) | 12.7 (2.93) | 12.3 (2.85) | 12.8 (3.10) | F(2,68) = 0.128 | 0.880 |
Self-reported language fluency, n | |||||
Fluent in Dutch only | 13 | 15 | 19 | χ2 = 7.357 | 0.118 |
Fluent in two languages | 9 | 3 | 17 | ||
Fluent in three language | 1 | 0 | 4 | ||
Duration of illness years, mean (SD) | 4.5 (5.55) | 5.1 (7.49) | MW = 189 | 0.871 | |
Total PANSS, mean (SD) | 52.0 (11.98) | 52.1 (8.57) | F(1,39) = 0.002 | 0.963 | |
PANSS positive | 10.7 (4.72) | 11.2 (2.98) | F(1,39) = 0.136 | 0.714 | |
PANSS negative | 14.0 (5.12) | 14.9 (4.96) | F(1,39) = 0.313 | 0.579 | |
PANSS general | 27.3 (6.51) | 26.1 (4.95) | F(1,39) = 0.424 | 0.519 | |
Psychotic disorder, n | χ2 = 4.244 | 0.236 | |||
Schizophrenia | 8 | 5 | |||
Schizoaffective disorder | 4 | 3 | |||
Schizophreniform disorder | 0 | 3 | |||
Psychosis NOS | 12 | 7 | |||
Chlorpromazine equivalent (mg), mean (SD) | 347.8 (217.87) | 518.6 (302.9) | MW = 107.5 | 0.056 | |
Antipsychotic medication, n | |||||
Amisulpride | 2 | ||||
Aripiprazole | 15 | ||||
Flupentixol | 1 | ||||
Haloperidol | 3 | ||||
Risperidone | 2 | ||||
Clozapine | 5 | ||||
Olanzapine | 5 | ||||
Paliperidone | 4 | ||||
Quetiapine | 4 | ||||
