Fig. 3: DNA hydrolysis by total IgG antibody.
From: DNA hydrolysing IgG catalytic antibodies: an emerging link between psychoses and autoimmunity
a–d Neuropsychiatric systemic lupus erythematosus (NP-SLE), schizophrenia (SCZ), bipolar disorder (BPD), and healthy control (HC) samples, respectively. Plasmid DNA, pUC18 (50 ng) was incubated with IgG (2 µg) for 2 h at 37 °C and visualised by ethidium bromide stain. Lanes: 1–5, IgG from patients; 6, IVIg & 7, DNA incubated alone. sc supercoiled DNA, rc relaxed circular DNA, ln linear DNA.
