Table 3 Region of interest (ROI) main analysis displaying the effects of cannabis and schizophrenia on each contrast of interest as well as the cannabis by schizophrenia interactions.

From: Interaction of schizophrenia and chronic cannabis use on reward anticipation sensitivity

Contrast

Anatomical labelling

  

Statistics

 

MNI coordinates

  
 

Label

Hemisphere

F

p (svc)

KE

x

y

z

Reward + Punishment > Neutral

        

 Cannabis

 Diagnosis

 Interaction

Reward > Punishment

        

 Cannabis

Putamen

R

15.89

0.009

4

24

5

−2

 

vAI

R

14.09

0.017

8

39

14

−8

 

dAI

R

14.42

0.015

6

39

17

−8

 Diagnosis

 Interaction

Thalamus

R

14.48

0.015

5

3

−19

7

High > Low + Neutral

        

 Cannabis

 Diagnosis

 Interaction

vAI

L

15.93

0.008

12

−39

−1

−5

 

dAI

L

14.46

0.014

3

−39

2

−2

 

pI

R

22.81

0.001

19

42

−10

13

  

L

16.05

0.008

16

−42

2

−8

  1. We applied family-wise error (FWE) correction adjusted for small volume [p (svc) < 0.05] within each of the independent ROIs at the voxel level (only ROIs with at least three contiguous voxels were considered significant).
  2. MNI Montreal Neurological Institute, svc small-volume correction, R right, L left, vAI ventral anterior insula, dAI dorsal anterior insula, pI posterior insula.