Table 2 List of demographic, clinical, and psychobiological characteristics in this study.

From: Surface area in the insula was associated with 28-month functional outcome in first-episode psychosis

Category

Features

Demographic characteristics

 

Age

Sex

JART25 IQ

Self SES

Parental SES

DUP (only in FEP)

Clinical characteristics

 

Symptom severity

GAF

PANSS 5 factor

Positive symptom

Negative symptom

Disorganized symptom

Excitement symptom

Emotional symptom

Medication equivalent dose

Chlorpromazine (antipsychotics)

Biperiden (antiparkinsonian)

Diazepam (anxiolytics)

Imipramine (antidepressant)

Self-report symptom severity

CES-D

WHOQOL-BREF

Physical domain

Psychological domain

Social relationships

Environment

General impression

Psychobiological characteristics

 

BACS-J

Verbal memory

Working memory

Motor speed

Verbal fluency

Attention and Processing speed

Executive function

Electrophysiological response

MMN amplitude in duration deviants

MMN amplitude in frequency deviants

Structural MRI

Cortical surface area (34 regions per hemisphere)*

Cortical thickness (34 regions per hemisphere)*

Subcortical volume (7 regions per hemisphere)*

fNIRS

Brain activity (8 regions per hemisphere)*

Total number of words generated during the task

Stanford Sleepiness Scale during the task

  1. *All regions were described in supplementary materials.
  2. JART25 the 25-item version of the Japanese Adult Reading Test, SES socioeconomic status, DUP duration of untreated psychosis, FEP first-episode psychosis, GAF the Global Assessment of Functioning, PANSS the Positive and Negative Syndrome Scale, CES-D the Center for Epidemiologic Studies Depression Scale, WHOQOL-BREF the 26-item brief version of the WHO Quality of Life Scale, BACS-J the Brief Assessment of Cognition in Schizophrenia Japanese version, MMN mismatch negativity, MRI magnetic resonance imaging, fNIRS functional near-infrared spectroscopy, SOFAS the Social and Occupational Functioning Assessment Scale.
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