Fig. 1: Symmetrized percentage change (SPC) in subcortical volumes 12 weeks after switching to clozapine treatment.

The graph presents the individual data points, together with the mean and standard error of the mean for each volume. Increases in lateral ventricle volume and decreases in caudate and putamen volume significantly differed from zero (* One sample T-test; P < 0.01). Please note SPC values are 4–5 fold greater than the percentage change (Table 2).