Fig. 1: Clusters showing differences in the LGI, cortical thickness between schizophrenia patients, and healthy controls at baseline. | Schizophrenia

Fig. 1: Clusters showing differences in the LGI, cortical thickness between schizophrenia patients, and healthy controls at baseline.

From: Prognostic associations of cortical gyrification in minimally medicated schizophrenia in an early intervention setting

Fig. 1

A, B Cortical statistical maps displaying an increased LGI in schizophrenia patients compared with healthy controls. The maps are shown for the bilateral supramarginal, left superior temporal, right posterior cingulate, and right paracentral, respectively. The horizontal bar shows p values after correction for multiple comparisons using Monte-Carlo simulations (threshold = 0.001); the blue regions show clusters where values are lower in schizophrenia and the red regions are clusters where values are higher in schizophrenia (vs. healthy controls) with p values from 0.05 to 0.00001. C Cortical statistical maps displaying the correlation between the LGI and clinical variables in the patient group at baseline. The horizontal bar shows p values after correction for multiple comparisons via Monte-Carlo simulations (threshold = 0.01), where the blue region shows Sch < HC with p values from 0.05 to 0.00001 and the red region shows Sch > HC with p values from 0.05 to 0.00001. DOI duration of illness in months, SANS schedule for assessment of negative symptoms; For the N-back task, accuracy measures were employed in the analysis.

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