Table 1 Demographic and clinical characteristics of the studies included in the meta-analysis.
From: Disrupted local functional connectivity in schizophrenia: An updated and extended meta-analysis
Study | Sample size (female) | Mean age (y) | Education (y) | Age at onset (y) | Duration (m) | PANSS | Medication (%) | First episode | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SZ | HC | SZ | HC | SZ | HC | Total | Positive | Negative | |||||
Bai et al. (2016) | 17 (3) | 17 (3) | 26.00 | 28.71 | 10.59 | 13.65 | NA | 40.29 | 82.06 | 15.29 | 24.88 | Drug free | Partial |
Cui et al. (2016)a | 17 (7) | 19 (9) | 21.24 | 23.79 | 13.71 | 14.74 | NA | 6.51 | 106.24 | 31.12 | 25.53 | Drug naive | Yes |
Cui et al. (2016)a | 15 (7) | 19 (9) | 22.53 | 23.79 | 13.40 | 14.74 | NA | 10.20 | 88.07 | 17.93 | 22.73 | Drug naive | Yes |
Gao et al. (2015) | 14 (5) | 14 (5) | 33.20 | 34.90 | 11.70 | 11.30 | NA | 9.20 | 74.10 | 16.40 | 22.60 | 100 | No |
Gao et al. (2018)a | 17 (7) | 29 (13) | 31.24 | 32.73 | 12.24 | 14.28 | 17.24 | 14.00 | 97.76 | 27.53 | 21.05 | 100 | No |
Gao et al. (2018)a | 17 (8) | 29 (13) | 36.82 | 32.73 | 13.76 | 14.28 | 29.18 | 7.88 | 37.29 | 9.53 | 8.41 | 100 | No |
Gao et al. (2020) | 57 (37) | 50 (27) | 31.63 | 28.38 | 12.86 | 15.64 | NA | 2.52 | 91.84 | 26.39 | 20.68 | Drug naive | No |
Gou et al. (2018) | 28 (12) | 21 (7) | 23.90 | 28.80 | 12.90 | 12.90 | NA | 15.10 | 85.70 | 17.80 | 21.00 | 100 | No |
Hu et al. (2016) | 42 (15) | 38 (13) | 24.86 | 24.76 | 10.48 | 11.05 | NA | 8.38 | 91.90 | 25.60 | 18.17 | Drug naive | Yes |
Jin et al. (2021) | 23 (12) | 24 (12) | 31.74 | 30.92 | 12.57 | 14.04 | NA | NA | NA | NA | NA | Drug naive | Yes |
Liu et al. (2006) | 18 (9) | 18 (9) | 23.67 | 24.44 | 14.11 | 15.28 | NA | 26.83 | 80.39 | NA | NA | Drug free | No |
Liu et al. (2016) | 27 (12) | 27 (9) | 25.44 | 27.44 | 12.30 | 12.96 | NA | 18.32 | 85.78 | 21.56 | 23.15 | 44 | No |
Lyu et al. (2021) | 32 (17) | 27 (17) | 16.75 | 16.40 | 10.19 | 10.11 | NA | 9.19 | 79.44 | 22.75 | 16.97 | Drug naive | Yes |
Shan et al. (2021) | 39 (12) | 20 (6) | 24.36 | 25.70 | 11.13 | 12.75 | NA | 5.00 | 103.90 | 23.82 | 27.28 | Drug free | No |
Wang et al. (2017) | 48 (27) | 31 (17) | 15.79 | 15.42 | 8.88 | 8.44 | NA | 5.35 | 75.10 | 21.50 | 17.92 | Drug naive | No |
Yan et al. (2020) | 69 (19) | 74 (29) | 24.22 | 26.27 | 13.23 | 14.69 | NA | 13.74 | 84.19 | 24.42 | 17.58 | Drug naive | Yes |
Yang et al. (2021) | 37 (28) | 39 (30) | 39.70 | 40.94 | 10.35 | 9.56 | 22.70 | 204.00 | 76.00 | 13.60 | 23.90 | 100 | No |
Yu et al. (2013) | 69 (36) | 62 (NA) | 31.70 | 29.90 | 14.20 | 15.30 | NA | 7.10 | 52.90 | 12.10 | 13.40 | 100 | No |
Yu et al. (2021) | 22 (11) | 60 (22) | 33.41 | 32.87 | 10.77 | 14.02 | NA | 15.48 | 93.50 | 27.18 | 19.82 | Drug naive | No |
Zhao et al. (2019) | 44 (13) | 26 (9) | 23.70 | 22.60 | 12.80 | 13.90 | NA | 12.00 | 102.00 | 15.30 | 24.70 | Drug naive | Yes |
BrainGluSchi | 58 (6) | 77 (27) | 35.26 | 38.86 | NA | NA | 20.17 | 181.08 | 61.02b (n = 53) | 16.36b (n = 56) | 15.67b (n = 55) | 90 | NA |
COBRE | 71 (13) | 84 (23) | 36.62 | 38.87 | NA | NA | 21.12b (n = 69) | 182.76b (n = 69) | 59.23b (n = 69) | 15.15 | 15.31b (n = 70) | 97 | NA |
NMorphCH | 34 (7) | 33 (16) | 33.94 | 29.33 | 13.00b (n = 26) | 16.23b (n = 22) | 18.75b (n = 25) | 188.76b (n = 25) | NA | NA | NA | NA | NA |
