Fig. 3: Density plots showing the distribution of SCZ factor and Affective factor PRS results. | Schizophrenia

Fig. 3: Density plots showing the distribution of SCZ factor and Affective factor PRS results.

From: Examining the source of increased bipolar disorder and major depressive disorder common risk variation burden in multiplex schizophrenia families

Fig. 3: Density plots showing the distribution of SCZ factor and Affective factor PRS results.

Dotted line shows the mean PRS value for population controls. a, b show the distribution of SCZ factor PRS for bipolar disorder (BIP) and major depressive disorder (MDD) respectively. c, d show the distribution of Affective factor PRS for BIP and MDD respectively. Each color represents one of the case definitions in the ISHDSF sample shown on the left side of each panel. One-sided p values after multiple testing correction are provided on the right side of each panel. All comparisons follow the hypothesis that ISHDSF members have higher PRS compared to population controls.

Back to article page