Table 1 Demographic, clinical, and imaging characteristics of the included studies.

From: Resting-state brain functional alterations and their genetic mechanisms in drug-naive first-episode psychosis

 

Demographic characteristics

Clinical characteristics (patients only)

Imaging characteristics

 

Number/female

Age, yr

  

PANSS score

   

Study

DFP

HC

DFP

HC

Drug status

Illness duration, mo

Total

Negative

Positive

Scanner

Software

Measures

Li et al.19

72/48

79/46

14.7 ± 1.78

14.3 ± 2.17

Drug naive

< 12

68.9 ± 18.4

16.3 ± 7.53

15.8 ± 5.19

3.0 T

DPABI

ALFF

Yan et al.20

69/19

74/29

24.22 ± 7.08

26.27 ± 6.97

Drug naive

13.74 ± 11.76

84.19 ± 8.25

17.58 ± 4.10

24.42 ± 3.88

3.0 T

DPARSF

ReHo

Zhao et al.21

44/13

26/9

23.7 ± 5.3

22.6 ± 3.7

Drug naive

12 ± 9.2

102 ± 16.7

24.7 ± 7.5

15.3 ± 3.3

3.0 T

DPARSF

ReHo

Wu et al.22

32/16

32/11

30.94 ± 8.25

31.37 ± 7.84

Drug naive

12 ± 9.2

77.38 ± 5.17

20.59 ± 3.46

20.00 ± 4.32

3.0 T

SPM8

fALFF

Liu et al.23

48/NA

31/NA

15.79 ± 1.64

15.42 ± 1.52

Drug naive

5.35 ± 6.12

75.10 ± 9.88

17.92 ± 6.95

21.50 ± 5.01

3.0 T

SPM8

ReHo

Lei et al.24

124/63

102/52

NA

NA

Drug naive

NA

NA

NA

NA

3.0 T

DPARSF

ALFF

Ren et al.25

100/59

100/59

24.30 ± 7.45

24.39 ± 7.58

Drug naive

6.25 ± 11.04

97.88 ± 17.75

18.84 ± 7.70

25.11 ± 5.97

3.0 T

DPARSF

ALFF

Scheef et al.26

11/3

25/13

32 ± 5

30 ± 6

Drug naive or free

NA

43.1 ± 8.5

21.4 ± 7.9

20.2 ± 2.9

3.0 T

SPM2

CBF

  1. DFP patients with drug-naive first-episode psychosis, HC healthy controls, PANSS Positive and Negative Syndrome Scale, NA not available, ALFF amplitude of low-frequency fluctuations, fALFF fractional amplitude of low-frequency fluctuations, ReHo regional homogeneity, CBF cerebral blood flow.