Table 1 Characteristics of studies included in the meta-analysis.

From: Influencing factors of medication adherence in schizophrenic patients: a meta-analysis

Author

Year

Study Design

Sample size N

Sample age M (SD)

Period

Diagnostic criteria

Influencing factors

References

Olfson, M.

2000

Cohort study

74

34.8 ± 9.7

18 months

DSM-IV

Substance abuse, past non-compliant behavior, family support

24

Acosta, F. J.

2009

Cohort study

102

42.4 ± 11.7

3 months

ICD-10

Insight, disease severity

47

Gearing, R. E.

2009

Cohort study

65

15.35 ± 2.08

at least 2 years

DSM-IV

Number of drugs

48

Hill, M.

2010

Cohort study

104

29.1 ± 12.0

4 years

DSM-IV

Alcohol and drug abuse, duration of illness

49

Lambert, M.

2010

Cohort study

605

15–29

18 months

DSM-IV

Number of medications, severity of illness, insight

50

Conti, V.

2012

Cohort study

4975

46.4 ± 15.3

1 years

ICD-10

Employment, city life, marriage, hospitalization

51

Hui, C. L. M.

2016

Cohort study

313

38.2 ± 8.4

6 months

DSM-IV

Severity of illness, hospitalization at onset, social support, attitudes to treatment

52

Anderson, J. P.

2017

Cohort study

308

/

1 years

DSM-IV

Psychological interventions, age, family support, alcohol and drug abuse, gender, education level, attitudes to treatment, social support

53

Conus, P.

2017

Cohort study

584

22.1 ± 3.4

18 months

DSM-IV

Severity of illness, level of education, social support

54

Daneault, J. G.

2019

Cohort study

421

14–35

2 years

DSM-IV

Alcohol or drug abuse, severity of illness

55

Desai, R.

2019

Cross-sectional study

496

/

/

ICD-9

Gender, family support, level of education

56

Rezansoff, S. N.

2019

Cohort study

1996

35.4 ± 9.4

17 months

ICD-9

Attitude to treatment, amount of medication

57

Tan, C. Z.

2019

Cohort study

445

26.3 ± 6.6

1 years

DSM-IV

Gender, family support, self-knowledge

58

Wang, D.

2020

Cross-sectional study

1189

34.22 ± 12.29

/

DSM-IV

Age, income, hospitalized at onset, severity of illness

59

Guitter, M.

2021

Cohort study

136

29.5 ± 9.9

1 years

ICD-10

Single, family support, hospitalized, other physical illness, active treatment

60

Rubio, J. M.

2021

Cohort study

512

/

8 years

ICD-10

Female, first hospitalization, other physical illness, age <25, substance abuse

61

Stockbridge, E.

2021

Cross-sectional study

1778

18–64

/

ICD-10

Age >50, education, level of mental health, substance abuse, other physical illness

62

Verdoux, H.

2021

Cross-sectional study

326

32.9 ± 0.4

/

DSM-V

Number of drugs, efficacy, side effects, quality of life, psychological interventions, level of education, self-knowledge

63

Cho, S. J.

2022

Cohort study

326917

/

6 months

ICD-10

Sex, hospitalized at onset, income

64

Kirchner, S. K.

2022

Cross-sectional study

1062

42.82 ± 12.98

/

DSM-IV

Attitude to treatment, medication dose, quality of life, alcohol or drug abuse

65