Table 3 FNC changes in patients with schizophrenia in the meta-analysis.

From: Transcriptional signatures of the whole-brain voxel-wise resting-state functional network centrality alterations in schizophrenia

Regions

Peak MNI coordinates

Cluster size (voxels)

SDM-Z value

P value

Heterogeneity test

Egger’s test (P value)

x

y

z

Q (P value)

Increased FNCs

 Right IPC/SMG/ANG

54

–54

36

1497

2.297

<0.0001

23.193 (0.508)

0.222

 Bilateral mPFC

–6

42

44

1620

2.118

<0.0001

18.494 (0.778)

0.870

 Right DLPFC

24

26

50

183

1.579

0.0007

20.714 (0.656)

0.095

Decreased FNCs

 Right insula

38

–8

–10

2354

–3.052

<0.0001

23.920 (0.466)

0.460

 Left insula

–30

6

4

1140

–1.767

0.0009

25.588 (0.374)

0.104

 Left PCG

–58

–8

40

963

–2.060

0.0002

21.866 (0.587)

0.737

 Right PCG

44

–22

46

238

–1.746

0.0010

18.776 (0.764)

0.592

 Right ITG

46

–64

–12

206

–1.796

0.0008

19.944 (0.700)

0.302

  1. ANG angular gyrus, DLPFC dorsolateral prefrontal cortex, FNC functional network centrality, IPC inferior parietal cortex, ITG inferior temporal gyrus, MNI Montreal Neurological Institute, mPFC medial prefrontal cortex, PCG postcentral gyrus, Q Cochran’s Q statistic, SDM seed-based d mapping, SMG supramarginal gyrus.