Fig. 2: Schematic of genes within the ‘Hepatic Fibrosis / Hepatic Stellate Cell Activation’ pathway that exhibit differential gene expression in HI-SCZ versus LI-SCZ. | Schizophrenia

Fig. 2: Schematic of genes within the ‘Hepatic Fibrosis / Hepatic Stellate Cell Activation’ pathway that exhibit differential gene expression in HI-SCZ versus LI-SCZ.

From: RNA-sequencing suggests extracellular matrix and vasculature dysregulation could impair neurogenesis in schizophrenia cases with elevated inflammation

Fig. 2

Genes in this top pathway identified by IPA have broad functional roles including regulation of the extracellular matrix, angiogenesis, growth factors, and immune cell function, all of which can influence the different cellular developmental stages of neurogenesis. Arrows next to gene names represent significantly increased (upward arrow) or decreased (downward arrow) gene expression in HI-SCZ compared to LI-SCZ.

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