Table 1 Cohort demographic details and statistical comparisons between inflammatory subgroups.
LI-SCZ n = 13 | HI-SCZ n = 14 | Statistics | |
|---|---|---|---|
Age at death in years | 43.23 ± 11.10 (19-61) | 50.21 ± 9.55 (35-68) | t(25)= -1.76, p = 0.09 |
pH | 6.56 ± 0.26 (6.10-6.91) | 6.49 ± 0.22 (6.18-6.93) | t(25) = 0.75, p = 0.46 |
PMI in hours | 26.38 ± 11.08 (9-42) | 28.82 ± 8.78 (16-47) | t(25) = -0.64, p = 0.53 |
RIN | 8.04 ± 0.64 (7.10-9.10) | 7.94 ± 0.33 (7.50-8.50) | t(17.75) = 0.52, p = 0.61 |
Sex | 8 M/5 F | 7 M/7 F | χ2 (1, N = 27) = 0.36, p = 0.55 |
Brain hemisphere | 5 Left, 8 Right | 6 Left, 8 Right | χ2 (1, N = 27) = 0.05, p = 0.82 |
Age of onset in years | 23.69 ± 7.32 | 19.43 ± 4.33 | t(19.18) = 1.83, p = 0.08 |
Duration of illness in years | 19.54 ± 13.24 | 30.79 ± 8.45 | t(25) = -2.65, p = 0.01 |
Lifetime antipsychotic dosea (mg) | 59,055 ± 108,506 | 143,458 ± 146,903 | t(25) = -1.69, p = 0.10 |
Antidepressant use | 3 | 3 | χ2 (1, N = 27) = 0.01, p = 0.92 |
Smoking at time of death | 7 Yes, 2 No, 4 Unknown | 13 Yes, 0 No, 1 Unknown | |
Suicide | 4 | 0 | |
Cause of death | Cardiac: 7, OD: 1, Pneumonia: 1, Asphyxiation: 2, Trauma: 2 | Cardiac: 6, OD:1, Pneumonia: 3, Cirrhosis:1, Pulmonary: 1, Asthma: 1, Pancreatitis:1 |