Table 1 Differences between BDNF Met-carriers and Val homozygotes at baseline.

From: Interaction between BDNF Val66Met polymorphism and mismatch negativity for working memory capacity in schizophrenia

 

Met-carriers

N = 37

Val homozygotes

N = 17

   

Mean

SD

Mean

SD

Statistic

df

P

Age

34.19

7.52

32.06

7.54

t = 0.967

52

0.338

Education

14.50

4.04

14.88

2.89

t = −0.35

52

0.728

Female/male

22/15

9/8

χ² = 0.202

1

0.653

Han nationality/non

33/4

16/1

NA

NA

1.000

Employment/non

15/22

8/9

χ² = 0.202

1

0.653

Marriage/non

16/21

5/12

χ² = 0.938

1

0.333

Current smoker/non

3/34

3/14

NA

NA

0.365

Clozapine user/non

8/29

1/16

χ² = 1.099

1

0.295

Chlorpromazine equivalents

441.18

314.11

443.88

213.70

t = −0.032

52

0.974

Duration of illness

12.14

8.51

9.48

7.09

t = 1.124

52

0.266

PANSS positive

9.73

3.84

7.65

1.54

t = 2.839

51

0.006

PANSS negative

12.86

4.60

11.47

3.56

t = 1.105

52

0.274

PANSS general

22.11

4.86

18.76

2.51

t = 3.325

51

0.002

PANSS total

44.70

9.14

37.88

6.19

t = 2.789

52

0.007

K_T2 (N: 34/17)

1.36

0.47

1.52

0.34

t = −1.235

49

0.223

K_T4 (N: 34/17)

1.59

0.80

2.11

0.59

t = −2.356

49

0.023

Filtering efficiency_T2 (N: 34/17)

0.27

0.28

0.26

0.29

t = 0.174

49

0.863

Filtering efficiency_T4 (N: 34/17)

0.70

0.43

0.84

0.44

t = −1.014

49

0.315

MMN amplitude (N: 36/17)

−2.83

1.64

−3.02

1.65

t = 0.377

51

0.708

  1. BDNF, brain-derived neurotrophic factor, PANSS positive and negative syndrome scale, K_T2 Cowan’s K under only two targets condition of the change detection task, K_T4 Cowan’s K under only four targets condition of the change detection task, Filtering efficiency_T2 filtering efficiency for two targets, Filtering efficiency_T4 filtering efficiency for four targets, MMN mismatch negativity.
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