Fig. 1: Participant disposition.

aThe safety population included all participants who received ≥1 dose of trial drug. bThe modified intent-to-treat population, used for all efficacy analyses, included all participants randomized who received ≥1 dose of trial drug, had a baseline Positive and Negative Syndrome Scale (PANSS) assessment, and had ≥1 postbaseline PANSS assessment. X/T xanomeline/trospium.