Table 1 Baseline demographics and characteristics (mITT population).
Parameter | Xanomeline/Trospium (n = 314) | Placebo (n = 326) |
|---|---|---|
Age (years), mean ± SD | 44.6 ± 10.7 | 43.7 ± 11.3 |
Sex, n (%) | ||
Male Female | 233 (74.2) 81 (25.8) | 250 (76.7) 76 (23.3) |
Race, n (%) | ||
Asian Black Native Hawaiian or Other Pacific Islander White Other | 4 (1.3) 225 (71.7) 1 (0.3) 83 (26.4) 1 (0.3) | 2 (0.6) 221 (67.8) 1 (0.3) 98 (30.1) 4 (1.2) |
Ethnicity, n (%) | ||
Hispanic or Latino Not Hispanic or Latino Not reported | 47 (15.0) 265 (84.4) 2 (0.6) | 34 (10.4) 291 (89.3) 1 (0.3) |
Country, n (%) | ||
United States Ukraine | 295 (93.9) 19 (6.1) | 300 (92.0) 26 (8.0) |
Weight (kg), mean ± SD | 88.9 ± 18.5 | 87.3 ± 18.6 |
BMI (kg/m2), mean ± SD | 29.2 ± 5.5 | 28.9 ± 5.4 |
PANSS total score, mean ± SD | 97.5 ± 9.0 | 97.0 ± 8.9 |
PANSS positive subscale score, mean ± SD | 26.6 ± 3.6 | 26.4 ± 3.4 |
PANSS negative subscale score, mean ± SD | 22.7 ± 3.8 | 22.6 ± 4.0 |
PANSS Marder negative factor, mean ± SD | 22.4 ± 4.5 | 22.3 ± 4.6 |
CGI-S score, mean ± SD | 5.1 ± 0.6 | 5.0 ± 0.6 |
