Table 2 AMP SCZ Schedule of Clinical Assessments.

Measure	Screening	BL	M1	M2	M3	M4	M5	M6	M7	M8	M9	M10	M11	M12	M18	M24	Conversion
PSYCHS/SOFAS/SCID5-PD-Schizotypal /FIGS/TBI/ medication use	✓C
Health and Medical Conditions Questionnaires	✓C	✓	✓	✓C	✓	✓	✓	✓	✓	✓	✓	✓	✓	✓C	✓	✓C
Demographics		✓C
PAS			✓
Adverse Events		✓C	✓	✓C	✓	✓	✓	✓	✓	✓	✓	✓	✓	✓C	✓	✓C
PSYCHS		✓C^*	✓	✓C	✓			✓						✓ C	✓	✓ C	✓
BPRS		✓C	✓	✓C	✓	✓	✓	✓	✓	✓	✓	✓	✓	✓	✓	✓	✓
CDSS		✓C	✓	✓C	✓			✓						✓	✓	✓	✓
NSI-PR		✓C	✓	✓C	✓			✓						✓	✓	✓	✓
OASIS		✓C	✓	✓C	✓			✓						✓	✓	✓	✓
CSSRS		✓C		✓C				✓						✓	✓	✓	✓
PROMIS-SD		✓C		✓C				✓						✓	✓	✓	✓
ASSIST		✓C		✓				✓						✓	✓	✓	✓
SCID-5-RVs (Psychosis, Mood, Substance Abuse)		✓C												✓		✓	✓
PGI-S		✓C	✓	✓C	✓			✓						✓	✓	✓	✓
GF: Social, GF: Role		✓C	✓	✓C	✓			✓						✓	✓	✓	✓
SOFAS	✓C	✓C	✓	✓C	✓			✓						✓C	✓	✓C	✓
PSS		✓C	✓	✓C	✓			✓						✓	✓	✓	✓
PD		✓C
PDS		✓C
PPS		✓C
^aMinutes for CHR participants	180	300	150	120	120	30	30	150	30	30	30	30	30	180	120	180	180

BL = baseline; ✓ =CHR participants; C=Community Control participants (only 5 of the 15 CC at each ProNET site, & 15 of the 100 CC at Melbourne will receive repeat assessments at M2).
PSYCHS Positive Symptoms and Diagnostic Criteria for the CAARMS Harmonized with the SIPS ^*skipped at baseline if within 21 days of Screening to reduce participant and rater burden, SOFAS Social and Occupational Functioning Scale, SCID5-PD Structured Clinical Interview for DSM-5 - Personality Disorders, FIGS Family Interview for Genetic Studies, TBI Traumatic Brain Injury, PAS Premorbid Adjustment Scale, BPRS Brief Psychiatric Rating Scale, CDSS Calgary Depression Scale for Schizophrenia, OASIS Overall Anxiety Severity And Impairment Scale, CSSRS Columbia Suicide Severity Rating Scale, PROMIS-SD Patient Reported Outcomes Measurement Information System-Sleep Disturbance, ASSIST Alcohol, Smoking and Substance Involvement Screening Test, SCID-5-RVs Structured Clinical Interview for DSM-5 - Research Version, PGI-S Patient Global Impression of Severity, GF Global Functioning, PSS Perceived Stress Scale, PD Perceived Discrimination, PDS Pubertal Development Scale, PPS Psychosis Polyrisk Score.
^aThis presents average time for a CHR participant (CCs take less time) at each clinical assessment completed by a trained and practiced clinical rater.

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