Fig. 1: Changes in the depression-like behaviors and the status of FA metabolism in the electrical stimulation-model mice.
From: External stress, formaldehyde, and schizophrenia: a new mouse model for mental illness research
A, B Location of double-electrode in the VTA of mice. VTA ventral tegmental area. C, D Anxiety-like behaviors assessed by the marble burying test and open-field test, respectively. E, F Depression-lie behaviors evaluated by the tail suspension test and sucrose preference test, respectively. G Short-term memory assessed by Y-maze test. H, I FDH activity in the PFC and VTA detected by ELISA kits. FDH formaldehyde dehydrogenase, PFC prefrontal cortex, VTA ventral tegmental area, ELISA enzyme-linked immunosorbent assay. J, K ALDH2 activity in the PFC and VTA detected by ELISA kits. L, M SARDH activity in the PFC and VTA detected by ELISA kits. SARDH sarcosine dehydrogenase. N, O FA levels in the PFC and VTA detected by NaFA probe. FA: formaldehyde. *p < 0.05; **p < 0.01; NS no statistical significance.
