Fig. 3: Identification of TIQ in vitro by HRMS and in vivo by HPLC. | Schizophrenia

Fig. 3: Identification of TIQ in vitro by HRMS and in vivo by HPLC.

From: External stress, formaldehyde, and schizophrenia: a new mouse model for mental illness research

Fig. 3

A FA probe- NaFA. B, C Change in FA levels detected by NaFA probe, FA formaldehyde, DA dopamine. D TIQ formation between FA and DA. TIQ tetrahydroisoquinoline. E TIQ identified by HRMS. HRMS high-resolution mass spectrometry. F TIQ in the brain quantified by HPLC. HPLC high-performance liquid chromatography. G Changes in TIQ levels in the ES-model mice. ES electrical stimulation. **p < 0.01.

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