Table 3 Test-retest reliability for electroencephalography-based and reaction time measures in community control and clinical high risk groups.

From: The electroencephalography protocol for the Accelerating Medicines Partnership® Schizophrenia Program: Reliability and stability of measures

Measure

Electrodes included in average

Community Control (n = 84)

Clinical High Risk (n = 571)

G-coefficienta

G-coefficient

Event-related potential measures

 AODb Target P300 (P3b)

CPz, CP1, CP2, Pz, P1, P2

0.66

0.72

 AOD Novel P300 (P3a)

FCz, FC1, FC2, Cz, C1, C2

0.74

0.70

 VODc Target P300 (P3b)

CPz, CP1, CP2, Pz, P1, P2

0.77

0.76

 VOD Novel P300 (P3a)

Cz, C1, C2, CPz, CP1, CP2

0.78

0.72

 Mismatch Negativity

Fz, F1, F2, FCz, FC1, FC2

0.73

0.78

Event-related oscillation measures

 40-Hz ASSRd Inter-trial Coherence

FCZ, FC1, FC2, Cz, C1, C2

0.68

0.68

 40-Hz ASSR Evoked Power

Fz, F1, F2, FCz, FC1, FC2

0.64

0.75

 40-Hz ASSR Total Power

FCZ, FC1, FC2, Cz, C1, C2

0.67

0.65

Power spectral density measures

 Resting EEGe (eyes open): Delta

Fz, FCz

0.80

0.77

 Resting EEG (eyes closed) Delta

Fz, FCz

0.86

0.79

 Resting EEG (eyes open): Theta

Fz, FCz

0.81

0.81

 Resting EEG (eyes closed) Theta

Fz, FCz

0.89

0.84

 Resting EEG (eyes open): Alpha

Pz, P1, P2, POz, PO3, PO4

0.88

0.85

 Resting EEG (eyes closed) Alpha

Pz, P1, P2, POz, PO3, PO4

0.85

0.79

 Resting EEG (eyes open): Beta

AF3, AF4, F3, F4, F5, F6, POz, PO3, PO4

0.66

0.62

 Resting EEG (eyes closed) Beta

AF3, AF4, F3, F4, F5, F6, POz, PO3, PO4

0.71

0.72

 Resting EEG (eyes open): Gamma

AFz, AF3, AF4, Fz, F3, F4, F5, F6

0.54

0.52

 Resting EEG (eyes closed) Gamma

AFz, AF3, AF4, Fz, F3, F4, F5, F6

0.44

0.49

Reaction time measures

 AOD Target Median Reaction Time

0.68

0.78

 VOD Target Median Reaction Time

0.67

0.79

  1. Note. G-coefficients are estimated for P300 and MMN amplitudes, 40-Hz ASSR measures, and for EEG absolute power spectral density for frequency bands Delta (1–3 Hz), Theta (4-7 Hz), Alpha (8-12 Hz), Beta (13-30 Hz), and Gamma (31-48 Hz).
  2. Participant samples are based on EEG sessions with quality control ratings ≥ 3.
  3. aG-Generalizability coefficient; an intraclass correlation coefficient reflecting test-retest reliability over baseline and month-2 EEG sessions.
  4. bAOD-auditory oddbal task.
  5. cVOD-visual oddbal task.
  6. dASSR-auditory steady state response.
  7. eEEG-electroencephalography.