Fig. 3: Suppression of p-tau in Alzheimer’s disease pathology by RA intake. | npj Science of Food

Fig. 3: Suppression of p-tau in Alzheimer’s disease pathology by RA intake.

From: Rosmarinic acid suppresses tau phosphorylation and cognitive decline by downregulating the JNK signaling pathway

Fig. 3

Paraffin sections were stained with anti-p-tau (AT8) and peroxidase-based labeling (brown) and counterstained with hematoxylin to visualize nuclei (violet). Immunohistochemistry for p-tau in the CA1 (a) and DG (b) regions of the hippocampus. The scale bar showed 100 μm in distance. c–d Percentage of p-tau-positive cells in CA1 (c) and DG (d). Bregma, −1.8 to −2.2 mm; slice thickness, 5 μm Data are shown as means ± standard error. Cont, n = 3; RA, n = 3, *p < 0.05.

Back to article page