Fig. 4: Remodeling of gut microbiota at the genus level by GC, GEO, and citral, and their relationship with aortic lesion and gut microbiota metabolites. | npj Science of Food

Fig. 4: Remodeling of gut microbiota at the genus level by GC, GEO, and citral, and their relationship with aortic lesion and gut microbiota metabolites.

From: Ginger essential oil and citral ameliorates atherosclerosis in ApoE−/− mice by modulating trimethylamine-N-oxide and gut microbiota

Fig. 4: Remodeling of gut microbiota at the genus level by GC, GEO, and citral, and their relationship with aortic lesion and gut microbiota metabolites.

Heatmap of the relative abundance of significantly different fecal microbiota using Kruskal–Wallis test (p < 0.05), and Spearman’s correlation analysis between gut microbiota components at the genus level and aortic lesion and gut microbiota metabolites. Pairwise statistical analyses were performed using an unpaired Wilcoxon signed-rank test CON vs. GC groups; Kruskal–Wallis test with Dunn’s multiple comparison test for comparing GC, GC + GEOLow, GC + GEOHigh, and GC + CIT. CON: control diet group, GC: Gubra Amylin NASH diet [GAN diet] + ʟ-carnitine in drinking water [1.3%] group, GC + GEOLow: GC + Ginger essential oil (GEO) [50 mg/kg bw/day] group, GC + GEOHigh: GC + GEO [100 mg/kg bw/day] group; GC + CIT: GC + Citral [20 mg/kg bw/day] group.

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