Table 1 Salivary proteins overrepresented in 9 rats without cheese LAB persistence at the end of the pre-diet period compared to the 9 rats with LAB persistence
From: Fermented food consumption modulates the oral microbiota
UniProt: accession number | Protein name | Mass (Da) | Anova (p value) | q -value | Fold change | Oxidations |
|---|---|---|---|---|---|---|
Protein degradation activity | ||||||
P40307 | Proteasome subunit beta type-2 | 22912.3 | 7.49E−05 | 6.65E−03 | 5.8 | |
P17220 | Proteasome subunit alpha type-2 | 25926.5 | 5.1E−04 | 2.10E−02 | 4.4 | |
P60901 | Proteasome subunit alpha type-6 | 27399.4 | 8.9E−04 | 2.33E−02 | 3.6 | |
A0A0G2K0 W9 | Proteasome subunit alpha type 7 | 27855.8 | 9.2E−04 | 2.33E−02 | 3.8 | |
P40112 | Proteasome subunit beta type-3 | 22949.0 | 1.42E−03 | 2.45E−02 | 5.4 | |
G3V7Q6 | Proteasome subunit beta type-5 | 28559.3 | 3.92E−03 | 3.34E−02 | 3.3 | |
P18422 | Proteasome subunit alpha type-3 | 28419.2 | 5.47E−03 | 3.89E−02 | 4.2 | |
Q6P9V6 | Proteasome subunit alpha type-5 | 26411.0 | 6.23E−03 | 4.12E−02 | 3.4 | |
P21670 | Proteasome subunit alpha type-4 | 29497.7 | 6.93E−03 | 4.40E−02 | 2.7 | |
Antioxidant and oxidoreductase activity | ||||||
A0A0G2JSH9 | Peroxiredoxin-2 | 21797.7 | 7.07E−05 | 6.65E−03 | 5.2 | |
P08010 | Glutathione S-transferase Mu 2 | 25702.6 | 1.22E−03 | 2.33E−02 | 3.4 | |
P07632 | Superoxide dismutase [Cu-Zn] | 15911.6 | 2.32E−03 | 2.85E−02 | 7.9 | |
P11232 | Thioredoxin | 11673.4 | 2.35E−03 | 2.85E−02 | 5.4 | |
Q9ESH6 | Glutaredoxin-1 | 11878.8 | 2.60E−03 | 2.91E−02 | 9.1 | |
Q63716 | Peroxiredoxin-1 | 22109.4 | 2.86E−03 | 2.99E−02 | 3.3 | |
D4A4Y2 | Hydroxysteroid (17-beta) dehydrogenase 14 | 28157.2 | 1.87E−05 | 4.97E−03 | 5.5 | |
O88989 | Malate dehydrogenase. cytoplasmic | 36460.0 | 1.82E−03 | 2.60E−02 | 3.3 | |
P97584 | Prostaglandin reductase 1 | 35695.0 | 2.62E−03 | 2.91E−02 | 3.0 | O/OH |
P04642 | L-lactate dehydrogenase A chain | 36450.5 | 5.47E−03 | 3.89E−02 | 2.6 | |
P04906 | Glutathione S-transferase P | 23438.8 | 6.72E−03 | 4.32E−02 | 2.8 | |
Binding activity | ||||||
F7F1J0 | Odorant-binding protein | 10744.3 | 3.96E−03 | 2.33E−02 | 2.9 | O/OH/diO/OH |
P20289 | von Ebner gland protein 1 | 19725.5 | 1.09E−03 | 2.33E−02 | 4.3 | O/OH |
Q05982 | Nucleoside diphosphate kinase A | 17182.0 | 3.84E−03 | 3.34E−02 | 5.3 | |
D3ZJV7 | Lipocalin 4 | 21646.1 | 1.15E−02 | 5.71E−02 | 2.2 | diO/OH |
D3ZK46 | Lipocalin 3 | 19557.6 | 3.94E−03 | 3.34E−02 | 2.5 | O/OH |
D3ZWC2 | BPI fold-containing family A. member 5 | 29169.3 | 1.65E−03 | 2.59E−02 | 5.2 | |
P02767 | Transthyretin | 15719.8 | 1.07E−03 | 2.33E−02 | 7.1 | |
G3V6G1 | Immunoglobulin joining chain | 17784.3 | 7.20E−03 | 4.51E−02 | 2.5 | |
B3EY86 | Lipocalin 11 | 20006.5 | 2.09E−03 | 2.79E−02 | 2.9 | O/OH |
P08699 | Galectin-3 | 27201.5 | 4.30E−03 | 3.42E−02 | 3.6 | |
F1M6Y6 | Lipocln_cytosolic_FA | 20372.5 | 2.80E−03 | 2.99E−02 | 3.0 | diO/OH |
Q9QYU9 | Odorant-binding protein | 19725.1 | 3.96E−03 | 3.34E−02 | 2.9 | O/HO |
A0A0G2JZ62 | Odorant-binding protein 2B | 20507.7 | 5.39E−03 | 3.89E−02 | 2.8 | O/OH/diO/OH |
P48199 | C-reactive protein | 25468.0 | 8.52E−03 | 4.78E−02 | 2.9 | |
P08937 | Odorant-binding protein | 19699.0 | 6.26E−03 | 4.12E−02 | 2.8 | O/OH/ diO/OH |
Hydrolase activity | ||||||
Q6Q0N1 | Cytosolic nonspecific dipeptidase | 52693.1 | 1.31E−03 | 2.38E−02 | 6.2 | |
A0A0G2K4B4 | Acid phosphatase. prostate | 47941.4 | 8.79E−03 | 4.83E−02 | 4.8 | |
Q6IN37 | GM2 ganglioside activator | 21493.0 | 1.65E−03 | 2.59E−02 | 4.0 | |
Q66HG3 | Beta-Ala-His dipeptidase | 54927.7 | 1.34E−03 | 2.38E−02 | 5.1 | |
D3ZZ65 | Caspase 14 | 28255.2 | 4.10E−03 | 3.34E−02 | 2.9 | |
D3ZSZ1 | Poly(U)-specific endoribonuclease | 47033.5 | 3.50E−03 | 3.34E−02 | 5.0 | |
F1M091 | Kallikrein | 27260.6 | 7.07E−04 | 2.10E−02 | 3.8 | |
Q6IE55 | Glandular kallikrein-10 | 31221.1 | 8.51E−03 | 4.78E−02 | 2.4 | |
P00697 | Lysozyme C-1 | 16729.0 | 7.40E−03 | 4.52E−02 | 7.7 | |
Lyase activity | ||||||
P19945 | 60 S acidic ribosomal protein P0 | 34215.4 | 9.84E−04 | 2.33E−02 | 4.6 | |
Q66H59 | N-acetylneuraminate lyase | 35115.4 | 1.78E−03 | 2.60E−02 | 3.6 | |
P06214 | Delta-aminolevulinic acid dehydratase | 36031.5 | 1.85E−03 | 2.60E−02 | 3.3 | |
Q6P7Q4 | Lactoylglutathione lyase | 20819.6 | 1.18E−03 | 2.33E−02 | 4.7 | |
F1MAA9 | Serpin family B member 3 | 35115.4 | 1.53E−03 | 2.60E−02 | 3.6 | O/OH |
Transferase activity | ||||||
P14668 | Annexin A5 | 35744.5 | 1.04E−04 | 7.96E−03 | 5.5 | |
P13221 | Aspartate aminotransferase | 46400.0 | 6.52E−04 | 2.10E−02 | 5.9 | |
P42930 | Heat shock protein beta-1 | 22892.6 | 7.55E−03 | 4.52E−02 | 5.0 | |
P16638 | ATP-citrate synthase | 120635.9 | 6.07E−03 | 4.12E−02 | 2.5 | |
Q9EQS0 | Transaldolase | 37436.0 | 8.72E−03 | 4.83E−02 | 3.0 | |
P27605 | Hypoxanthine-guanine phosphoribosyltransferase | 24477.2 | 5.80E−05 | 6.65E−03 | 4.0 | |
P85973 | Purine nucleoside phosphorylase | 32301.9 | 5.58E−04 | 2.10E−02 | 3.1 | |
P22283 | Cystatin-related protein 2 | 21013.4 | 5.72E−03 | 4.01E−02 | 17.9 | |
Q497B0 | Omega-amidase NIT2 | 30700.9 | 7.48E−03 | 4.52E−02 | 5.7 | |
Regulatory and structural activity | ||||||
P02401 | 60 S acidic ribosomal protein P2 | 11691.9 | 4.52E−07 | 2.41E−04 | 17.1 | |
D3ZAJ1 | Cystatin A (Stefin A) | 11034.5 | 6.41E−03 | 4.17E−02 | 5.0 | |
F1LQM1 | Major urinary protein 5 | 20978.1 | 4.73E−03 | 3.65E−02 | 3.2 | |
Q5U206 | Calmodulin-like protein 3 | 16802.5 | 8.40E−03 | 4.78E−02 | 9.0 | |
Isomerase activity | ||||||
P25113 | Phosphoglycerate mutase 1 | 28831.9 | 2.62E−03 | 2.91E−02 | 3.8 | |
D3ZKA0 | Serine (Or cysteine) peptidase inhibitor | 44249.2 | 2.48E−03 | 2.91E−02 | 4.2 | |
D4A7L6 | Ribose-5-phosphate isomerase | 32471.9 | 3.46E−03 | 3.34E−02 | 3.8 | |
Other functions | ||||||
P07151 | Beta-2-microglobulin | 13719.9 | 3.95E−03 | 3.34E−02 | 2.7 | |
Q5I0D1 | Glyoxalase domain-containing protein 4 | 33267.6 | 1.66E−04 | 1.09E−02 | 6.1 | |
A0A096MJ41 | FAM3 metabolism-regulating-signalling molecule B | 26407.3 | 4.80E−03 | 3.66E−02 | 2.9 | |
D4AE00 | AP-3 complex subunit beta | 119142.3 | 4.04E−03 | 3.34E−02 | 3.2 | |
D4A0S3 | Proline-rich 4 | 26856.1 | 5.34E−04 | 2.10E−02 | 4.2 | O/OH |
P50116 | Protein S100-A9 | 13144.9 | 4.00E−03 | 3.34E−02 | 3.4 | |
Q9JJI3 | Alpha-2u globulin | 20650.7 | 2.29E−03 | 2.85E−02 | 3.2 | diO/OH |
