Fig. 2: ALSL supplementation increased insulin sensitivity, improved insulin resistance, and modulated serum lipid levels in HFD-fed mice.

A Intraperitoneal glucose tolerance test (IGTT) (2 g/kg body weight). B Area under the IGTT curve (AUC). C HOMA-IR was calculated using the following formula: fasting blood glucose (mmol/L) × fasting insulin (mU/L)/22.5. D Insulin tolerance test (ITT), E AUC of ITT, F HOMA-B was calculated using the following formula: (20 × fasting insulin (mU/L))/(fasting blood glucose (mmol/L)–3.5). G fasting serum glucose. H fasting serum insulin. I serum free fatty acids (FFA). J glycated hemoglobin (HbA1c). K–N the content of LDL-C, TCHO, HDL-C, TC, respectively. The number of mice tested was 12 (A–F) and 8 (G–N). Data are expressed as mean ± SD, a, b, c and d means significant difference (p < 0.05).