Fig. 10: The effect of BBR on amyloid plaques and glial reactivity in 5×FAD mice.
From: Network pharmacology study on the mechanism of berberine in Alzheimer’s disease model

5×FAD mice were administrated with NS and BBR for 8 weeks and processed to immunofluorescence assay with anti-6E10 antibody for amyloid plagues (A), anti-Iba1 antibody for microglia (B), and anti-GFAP antibody for astrocytes (C). D Statistical results for the fluorescent intensity of all three immunostaining. n = 6.