Fig. 7: Diet with lower Phgg (L-Phgg) also exhibited augmented colitis. | npj Science of Food

Fig. 7: Diet with lower Phgg (L-Phgg) also exhibited augmented colitis.

From: Processed dietary fiber partially hydrolyzed guar gum increases susceptibility to colitis and colon tumorigenesis in mice

Fig. 7

a Experiment timeline: 4-week-old WT mice were maintained on either a control (Con) or a Low-Phgg diet for 4 weeks. Afterwards, both groups received 1.4% (w/v) DSS in their drinking water for 7 days. b Percent change in body weight. c Gross colon appearance. d Colon length. e Spleen weight as a percent of body weight. Serum levels of f SAA and g Lcn2. h Colonic level Lcn2. i Representative images of H&E (original magnification, ×50), Alcian blue (original magnification, ×100), and Muc2 (green, original magnification, ×200) staining. Values are presented as mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001.

Back to article page